Gene-level annotation data used to build Cytoscape node metadata.
Format
Data frame with 24339 rows and 8 columns:
- Gene.Name
HGNC gene symbol.
- Approved.Name
Approved gene name.
- Hugo.Gene.Family
Gene family annotation.
- HPRD.Function
Functional annotation from HPRD.
- nodeType
Node classification used for Cytoscape styling.
- Domains
Protein domain annotations.
- Compartment
Subcellular compartment labels.
- Compartment.Overview
Simplified compartment grouping.
Examples
head(function_key)
#> Gene.Name Approved.Name
#> 1 A1BG alpha-1-B glycoprotein
#> 2 A1CF APOBEC1 complementation factor
#> 3 A2LD1 undefined
#> 4 A2M alpha-2-macroglobulin
#> 5 A2ML1 alpha-2-macroglobulin-like 1
#> 6 A3GALT2 alpha 1,3-galactosyltransferase 2
#> Hugo.Gene.Family
#> 1 Immunoglobulin-like domain containing
#> 2 RNA binding motif containing
#> 3 undefined
#> 4 undefined
#> 5 undefined
#> 6 Glycosyltransferase family 6
#> HPRD.Function
#> 1 Molecular function unknown (GO:0005554)
#> 2 RNA binding (GO:0003723)
#> 3 Molecular function unknown (GO:0005554)
#> 4 Protease inhibitor activity (GO:0030414)
#> 5 Protease inhibitor activity (GO:0030414)
#> 6 Galactosyltransferase activity (GO:0008378)
#> nodeType Domains Compartment
#> 1 undefined IGC2 undefined
#> 2 RNA binding and processing protein RRM RNA-associated; nucleus
#> 3 undefined undefined undefined
#> 4 undefined A2M cytosol; secretion
#> 5 undefined undefined undefined
#> 6 undefined TM undefined
#> Compartment.Overview
#> 1 plasma.membrane
#> 2 RNA.associated
#> 3 undefined
#> 4 plasma.membrane
#> 5 plasma.membrane
#> 6 undefined